Bioassay Technology Laboratory's DOCK4 Rabbit Polyclonal Antibody is a Rabbit Polyclonal antibody. This antibody has been shown to work in applications such as: Western Blot.
Description
This gene is a member of the dedicator of cytokinesis (DOCK) family and encodes a protein with a DHR-1 (CZH-1) domain: a DHR-2 (CZH-2) domain and an SH3 domain. This membrane-associated: cytoplasmic protein functions as a guanine nucleotide exchange factor and is involved in regulation of adherens junctions between cells. Mutations in this gene have been associated with ovarian: prostate: glioma: and colorectal cancers. Alternatively spliced variants which encode different protein isoforms have been described: but only one has been fully characterized